Download E-books Statistics in Clinical Vaccine Trials PDF

By Jozef Nauta

This monograph deals well-founded education and services at the statistical research of information from scientific vaccine trials, i.e., immunogenicity and vaccine box efficacy stories. The book's scope is sensible instead of theoretical. It opens with introductory chapters at the immunology of vaccines to supply readers with the required heritage wisdom. It then maintains with an in-depth exploration of the statistical method. Many real-life examples and SAS codes are offered, making program of the equipment elementary. issues mentioned contain greatest chance estimation for censored antibody titers, ANCOVA for antibody values, research of equivalence and non-inferiority immunogenicity trial info, research of information from vaccine box efficacy trials (including information from experiences with recurrent an infection data), becoming defense curves to information of problem or box efficacy reports, and the research of vaccine protection information.

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