By Beth Rockmill (auth.), Scott Keeney (eds.)
The detailed chromosome dynamics of meiosis have involved scientists for good over a century, yet lately there was a proliferation of latest facts in regards to the pairing, recombination, and segregation of chromosomes. In Meiosis, professional researchers discover contemporary advances in 3 major components: quantitative genetic equipment for research of homologous recombination and chromosome pairing, improvement of direct actual assays for DNA intermediates and items of recombination, and cytological equipment for characterizing chromosome behaviors and the styles through which particular proteins go together with meiotic chromosomes. Meiosis: quantity 2, Cytological Methods, information equipment for getting ready and studying meiotic tissues, cells, and chromosomes through electron microscopy, oblique immunofluorescence, fluorescent in situ hybridization, and live-cell imaging. The tools during this quantity are grouped for comfort by way of normal forms of organisms: fungi, crops and small animals (mostly invertebrates), and mammals. Composed within the hugely profitable equipment in Molecular Biology(tm) sequence layout, each one bankruptcy features a short creation, step by step tools, a listing of valuable fabrics, and a Notes part which stocks pointers on troubleshooting and heading off recognized pitfalls.
Comprehensive and state-of-the-art, Meiosis: quantity 2, Cytological equipment is a necessary guidebook, offering up to date and important new protocols for the examine of meiotic chromosome dynamics.
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